In our system temperature and pH are controlled. Furthermore, pH can be actively controlled, meaning that we are not simply setting a 5% CO2 environment but adapting the CO2 concentration to keep the pH at the desired target value set by the user.

Automation – The OSPIN bioreactor system is fully automated, meaning for example that the medium is automatically exchanged and you don’t have to go to the lab on a Sunday to feed your cells.

Data accessibility – All process data, like sensor data and process settings, are saved in the OSPIN cloud and are accessible from everywhere. You can monitor your bioreactor from your desk, your home or a conference location.

Functionalities can upgraded – Extra functionalities, such as glucose and lactate measurement, can be easily added in a second step to the system. You can start simple and later on, when your bioprocess needs more monitoring and controlling, you can add extra sensors, actuator and controllers to the device.

To seed cells into the bioreactor system, the autoclaved fluid path has to be assembled in a sterile flow hood and the tissue chamber seeded with cells. Once the fluidic path is closed it can be placed into the OSPIN bioreactor system – outside of the flow hood – without risking contamination. Automated cultivation of the cells can then start.

In our system you can control

• temperature
• pH
• glucose
• medium exchange reate
• oxygen concentration

Additionally, cells can be mechanically and electrically stimulated.

Upon request we can integrate other sensors & actuators

 

We are currently developing the functionality to automatically passage cells.