BIOREACTOR PLATFORM

Our modular and scalable bioreactor platform supports a wide range of bioprocess applications. Through fully automated processes as well as the user-centered interface you will save time and increase throughput.

We build what you need

We are developing a universal bioprocessing platform where different functional modules such as sensors or actuators can be combined freely to create customized systems covering a wide range of different applications. Through an intuitive browser-based user interface, you can design automated bioprocesses, which can then be automatically carried out by your device. OSPIN cloud services allow you to monitor, manage and analyze the resulting bioprocess data online. Modularity and scalability allow the platform to evolve with your project from R&D to an industrial application.

Interested? Contact us!

 

Application Examples

Multi-purpose Bioreactor

Cardiac Tissue Bioreactor

Blood Vessel Bioreactor

Modularity

Customize your device by choosing between a wide range of modules.

Improved process reproducibility

Save time and money.

Cloud based data processing

Work with the next generation of bioprocess engineering.

Better time to market

Be faster than your competitors.

Bioprocessing Modules

 

Peristaltic Pump

Continuous perfusion of the tissue chamber.

The flowing medium improves the mass transfer of nutrients and oxygen and therefore results in a more physiological environment, when compared to static cells culture systems.

Medium Exchange

Forget changing medium on Sunday.

Define a rate with which fresh medium is added and used medium is removed. Alternatively you can control the exchange according to measured values such as pH, glucose, lactate, etc.

Temperature Control

Heat your tissue and medium to a desired temperature.

Moreover, you can freely choose different points in which the medium temperature is measured and controlled.

Gas Exchange/Bubble Trap

Dissolve soluble gases and remove unwanted air bubbles.

You can equilibrate dissolved gases with a given atmosphere. Depending on the gas mixture you feed into the system you can for instance ascertain a defined medium pH or recreate specific cellular environments such as hypoxia.

pH/pO2 Control

Control the pH and the pO2 of the medium.

For measuring we integrated Mettler Toledo probes. In conjunction with Gas Exchange you can also tightly control these values.

Metabolite Monitor

Continuously monitor glucose concentration.

Based on continuous monitoring you can actively control concentrations in the circulating medium by selectively feeding metabolites into the system.

Mechanical Stimulation

Bring your tissue to the fitness studio and monitor its progresses.

Are you working with muscle cells? This module can stretch or compress your tissue by different means, such as linear motors or pressurized air. You can also measure the applied force and the force produced by the cells.

Heart Beat Pump

Expose your tissue to a physiological heart beat.

Enables perfusion with any desired dynamic pressure or flow profile. You can for instance reproduce pulsatile flow such as created by a beating heart. In addition floating cells are not squeezed.

Electrophysiology

Stimulate and measure your tissue electrical activity.

Are you working with neurons, muscle cells or any other electrically active tissue? This module can measure biopotentials and for electrical stimulation you can choose pulse shape, amplitude, pulse length and frequency.

Microscope

Observe your tissue while your bioreactor is in operation.

Or let the microscope take pictures automatically at a given interval (for example every hour). Images series will then be ready to be analyzed.

User friendly User Interface

Through our intuitive browser-based user interface, you can design automated bioprocesses, which can then be automatically carried out by your device. OSPIN cloud services allow to monitor, manage and analyze the resulting bioprocess data online. Additional value can be created by connecting the data with other cloud services such as electronic lab books.

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