Biomimetic tissue engineering of vascular systems.

Set the right pulse for your cells.

To assure the formation of a biomimetic blood vessel structure our system creates the right biomechanical environment to trigger self-organisation of the cells in 3D. Shear stress induced by flow causes endothelial cells to concentrate on the inner surface of the blood vessel model and form a confluent layer. Whereas smooth muscle cells detect periodic changes of tension associated with a pulsatile pressure profile, which leads to a tangential orientation of the cells around the blood vessel.

OSPIN Modules

OSPIN’s modular approach allows you to combine generic bioprocessing modules such as temperature and pH control with application specific modules.

Heart Beat Pump

Control the heart rhythm of your bioreactor system and expose your cells to defined pulsatile pressure and flow profiles.